35 YR OLD MALE WITH HYPOGLYCEMIA AND ALTERED SENSORIUM.

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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.


A 35 year old male patient was brought to casuality with the chief complaints of :


Unresponsiveness since 4 am morning

Abdominal distension since 1 week

Pedal edema since 1 week

Yellowish discoloration of eyes. 


HISTORY OF PRESENT ILLNESS:

Patient was apparently asymptomatic 6 yrs back then he developed yellowish discoloration of eyes , swelling of both legs and abdominal distension, went to local hospital and diagnosed with Chronic liver disease.

Since then patient was on irregular medication and continued taking alcohol intermittently.(Patient is an known alcoholic since 20 years.) 

History of increased bilateral pedal odema which is pitting in nature since 1 week . 

History of increased abdominal distension since 1 week

Since 4 days, patient has c/o fever subsided after medication. 

C/o loose stools 4-5 episodes per day,no h/o malena , pain abdomen

C/o nausea and loss of appetite

C/o altered sensorium not responding to commands

No h/o weakness and no h/o involuntary movements


PAST HISTORY:

He was diagnosed with Portal hypertension and Grade2 oesophageal varices.

Not a known case of HTN , DM , Asthma , Epilepsy. 


PERSONAL HISTORY:

 Diet - Mixed

Appetite - Decreased

Sleep - adequate

Bowel & bladder movements - Normal

Addictions - Regular intake of alcohol (180ml) since 20 years



FAMILY HISTORY:

No similar complaints in the family


GENERAL EXAMINATION:

Patient is conscious , coherent and cooperative &

Thin built and malnourished.

Icterus present


No pallor , cyanosis , clubbing and lymphadenopathy. 

Bilateral pitting type of pedal odema present


Vitals:

Temp : Continuous at 100 F

BP : 100/80 mm Hg

PR : 105 bpm

RR : 25 cpm

GRBS : 33 mg/dl

SpO2 : 91% at Room air


SYSTEMIC EXAMINATION:

CVS : S1S2 + , No murmurs

RS.  : BAE + , Normal vesicular breath sounds heard. 

P/A : abdominal distension is presentAltered coagulation signs: 



INVESTIGATIONS:



PROVISIONAL DIAGNOSIS:

HEPATIC ENCEPHALOPATHY SECONDARY TO LIVER FAILURE

RECURRENT HYPOGLYCEMIA

K/C/O CHRONIC LIVER DISEASE WITH GROSS ASCITES AND SPLENOMEGALY(PORTAL HTN)

Secondary bacterial peritonitis

Pre renal AKI (hepatorenal syndrome?) 

Deranged coagulation time 



TREATMENT:

INJ.LASIX 20 MG/IV/BD

TAB.ALDACTONE 50 MG/RT/BD

INJ.25% DEXTROSE 100ML/IV/SOS IF GRBS<60 MG/DL

SYP. LACTULOSE 20 ML/PO/BD

INJ. THIAMINE 1 AMP IN 100 ML NS/IV/TID

GRBS CHECK HOURLY

BP/PR/TEMP CHARTING HOURLY

T. UDILIV 300 MG/ RT/BD

SYP. HEPAMERZ 2 TBSP/RT/BD

T RIFAXIMIN 550 MG /RT/BD

ENEMA 12 TH HOURLY

STRICT I/O CHARTING

INJ.CEFOTAXIME 2G /IV/BD

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